Structure of PDB 7nwr Chain B

Receptor sequence
>7nwrB (length=426) Species: 818 (Bacteroides thetaiotaomicron) [Search protein sequence]
EIKPATGRLGVLVVGVGGAVATTMIVGTLASRKGLAKPIGSITQLATMRM
ENNEEKLIKDVVPLTDLNDIVFGGWDIFPDNAYEAAMYAEVLKEKDLNGV
KDELEAIKPMPAAFDHNWAKRLNGTHIKKAATRWEMVEQLRQDIRDFKAA
NNCERVVVLWAASTEIYIPLSDEHMSLAALEKAMKDNNTEVISPSMCYAY
AAIAEDAPFVMGAPNLCVDTPAMWEFSKQKNVPISGKDFKSGQTLMKTVL
APMFKTRMLGVNGWFSTNILGNRDGEVLDDPDNFKTKEVSKLSVIDTIFE
PEKYPDLYGDVYHKVRINYYPPRKDNKEAWDNIDIFGWMGYPMEIKVNFL
CRDSILAAPIALDLVLFSDLAMRAGMCGIQTWLSFFCKSPMHDFEHQPEH
DLFTQWRMVKQTLRNMIGEKEPDYLA
3D structure
PDB7nwr Characterization of inositol lipid metabolism in gut-associated Bacteroidetes.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.5.1.4: inositol-3-phosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B V17 G18 G21 A22 V23 D79 I80 F81 A115 A164 A165 S166 T167 Y201 D241A F242 S244 R276 D277 K290 D356 A360 V14 G15 G18 A19 V20 D76 I77 F78 A112 A161 A162 S163 T164 Y198 D238 F239 S241 R273 D274 K287 D353 A357
Gene Ontology
Molecular Function
GO:0004512 inositol-3-phosphate synthase activity
GO:0016853 isomerase activity
Biological Process
GO:0006021 inositol biosynthetic process
GO:0008654 phospholipid biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7nwr, PDBe:7nwr, PDBj:7nwr
PDBsum7nwr
PubMed35725777
UniProtQ8A7J8|INO1_BACTN Inositol-3-phosphate synthase 1 (Gene Name=BT_1526)

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