Structure of PDB 7ns5 Chain B

Receptor sequence
>7ns5B (length=312) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
IITLPRFIIEHQKQFKNATGDFTLVLNALQFAFKFVSHTIRRAELVNLVG
LAKLDVLGDEIFINAMRASGIIKVLVSEEQEDLIVFPTSYAVCCDPIDGS
SNLDAGVSVGTIASIFRLLPDSSGTINDVLRCGKEMVAACYAMYGSSTHL
VLTLGDGVDGFTLDTNLGEFILTHPNLRIPPQKAIYSINEGNTLYWNETI
RTFIEKVKQPQADNNNKPFSARYVGSMVADVHRTFLYGGLFAYPCDKKSP
NGKLRLLYEAFPMAFLMEQAGGKAVNDRGERILDLVPSHIHDKSSIWLGS
SGEIDKFLDHIG
3D structure
PDB7ns5 GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.11: fructose-bisphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B E108 D128 D131 E292 E78 D95 D98 E259
BS02 MG B E108 D128 I130 D131 E78 D95 I97 D98
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity
GO:0042578 phosphoric ester hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005986 sucrose biosynthetic process
GO:0006000 fructose metabolic process
GO:0006002 fructose 6-phosphate metabolic process
GO:0006094 gluconeogenesis
GO:0030388 fructose 1,6-bisphosphate metabolic process
GO:0072593 reactive oxygen species metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ns5, PDBe:7ns5, PDBj:7ns5
PDBsum7ns5
PubMed33905682
UniProtP09201|F16P_YEAST Fructose-1,6-bisphosphatase (Gene Name=FBP1)

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