Structure of PDB 7nq4 Chain B

Receptor sequence
>7nq4B (length=381) Species: 9606 (Homo sapiens) [Search protein sequence]
MKLSLTKVVNGCRLGKIKNLGKTGDHTMDIPGCLLYTKTGSAPHLTHHTL
HNIHGVPAMAQLTLSSLAEHHEVLTEYKEGVGKFIGMPESLLYCSLHDPV
SPCPAGYVTNKSVSVWSVAGRVEMTVSKFMAIQKALQPDWFQCLSDGEVS
CKEATSIKRVRKSVDRSLLFLDNCLRLQEESEVLQKSVIIGVIEGGDVME
ERLRSARETAKRPVGGFLLDGFQGNPTTLEARLRLLSSVTAELPEDKPRL
ISGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFSFDYQEITSFEI
NLKEKKYQEDFNPLVRGCSCYCCKNHTRAYIHHLLVTNELLAGVLLMMHN
FEHYFGFFHYIREALKSDKLAQLKELIHRQA
3D structure
PDB7nq4 Structural and functional insights into human tRNA guanine transgylcosylase.
ChainB
Resolution2.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B V118 N371 L373 V118 N338 L340
BS02 ZN B C351 C353 C356 H382 C318 C320 C323 H349
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005515 protein binding
GO:0008479 tRNA-guanosine(34) queuine transglycosylase activity
GO:0016763 pentosyltransferase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0101030 tRNA-guanine transglycosylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0120507 tRNA-guanine transglycosylase complex
GO:1990234 transferase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7nq4, PDBe:7nq4, PDBj:7nq4
PDBsum7nq4
PubMed34241577
UniProtQ9H974|QTRT2_HUMAN Queuine tRNA-ribosyltransferase accessory subunit 2 (Gene Name=QTRT2)

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