Structure of PDB 7nlk Chain B

Receptor sequence
>7nlkB (length=298) Species: 208963 (Pseudomonas aeruginosa UCBPP-PA14) [Search protein sequence]
AEAGGPGGNQKIGKYTYGSDYGPLIVNDRCEMDDGNVITVDMNGSTNDSK
TTPFRFACPTNTYKQVNGAYSPLNDAHFFGGVVFNLYRDWFGTSPLTHKL
YMKVHYGRSVENAYWDGTAMLFGDGATMFYPLVSLDVAAHEVSHGFTEQN
SGLIYRGQSGGMNEAFSDMAGEAAEFYMRGKNDFLIGYDIKKGSGALRYM
DQPSRDGRSIDNASQYYNGIDVHHSSGVYNRAFYLLANSPGWDTRKAFEV
FVDANRYYWTATSNYNSGACGVISSAQNRNYSAADVTRAFSTVGVTCP
3D structure
PDB7nlk LasB, N-aryl-2-butylmercaptoacetamide inhibitor complex
ChainB
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.26: pseudolysin.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B H140 H144 E164 H140 H144 E164
BS02 CA B D136 E172 E175 D183 L185 D136 E172 E175 D183 L185
BS03 UHK B H140 R198 H223 H140 R198 H223
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function

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Biological Process
External links
PDB RCSB:7nlk, PDBe:7nlk, PDBj:7nlk
PDBsum7nlk
PubMed
UniProtQ02RJ6|ELAS_PSEAB Elastase (Gene Name=lasB)

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