Structure of PDB 7ni7 Chain B

Receptor sequence
>7ni7B (length=246) Species: 9606 (Homo sapiens) [Search protein sequence]
NDYCQHFVDTGHRPQNFIRDRELIRLKDELIAKSNTPPMYLQADIEAFDI
RELTPKFDVILLEPPLEEYYRETKCWTWDDIMKLEIDEIAAPRSFIFLWC
GSGEGLDLGRVCLRKWGYRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTK
EHCLMGIKGTVVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLF
GRDSTIRPGWLTVGPTLTNSNYNAETYASYFSAPNSYLTGCTEEIE
3D structure
PDB7ni7 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D157 H332 H336 D28 H185 H189
External links
PDB RCSB:7ni7, PDBe:7ni7, PDBj:7ni7
PDBsum7ni7
PubMed
UniProtQ9HCE5|MET14_HUMAN N6-adenosine-methyltransferase non-catalytic subunit (Gene Name=METTL14)

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