Structure of PDB 7nh7 Chain B

Receptor sequence
>7nh7B (length=120) Species: 31631 (Human coronavirus OC43) [Search protein sequence]
SSILSLCAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPD
ATTSQDSYGGASVCIYCRARVEHPDVDGLCKLRGKFVQVPVGIKDPVSYV
LTHDVCRVCGFWRDGSCSCV
3D structure
PDB7nh7 OC43 coronavirus methyltransferase
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.50: mRNA guanylyltransferase.
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.4.22.69: SARS coronavirus main proteinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C116 C119 C127 C129 C106 C109 C117 C119
BS02 ZN B C74 C77 H83 C90 C64 C67 H73 C80
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008270 zinc ion binding
Biological Process
GO:0019079 viral genome replication

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:7nh7, PDBe:7nh7, PDBj:7nh7
PDBsum7nh7
PubMed
UniProtP0C6U7|R1A_CVHOC Replicase polyprotein 1a (Gene Name=1a)

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