Structure of PDB 7ndj Chain B

Receptor sequence
>7ndjB (length=192) Species: 10090 (Mus musculus) [Search protein sequence]
GENLRPVVINGSNVAMSHGNKEVFSCRGIKLAVDWFLERGHKDITVFVPA
WRKEQSRPDALITDQEILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVK
LAFESDGIIVSNDNYRDLANEKPEWKKFIDERLLMYSFVNDKFMPPDDPL
GRHGPSLDNFLRKKPIVPEHKKQPCPYGKKCTYGHKCKYYHP
3D structure
PDB7ndj PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
ChainB
Resolution1.649 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna B Y308 C312 T313 Y314 K317 Y177 C181 T182 Y183 K186
BS02 ZN B C306 C312 C318 H322 C175 C181 C187 H191
External links
PDB RCSB:7ndj, PDBe:7ndj, PDBj:7ndj
PDBsum7ndj
PubMed33950203
UniProtQ5DTV4|ZC12C_MOUSE Probable ribonuclease ZC3H12C (Gene Name=Zc3h12c)

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