Structure of PDB 7n6u Chain B

Receptor sequence
>7n6uB (length=595) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
TEKLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPN
PQEVVLENVTEHFNMWKNNMVEQMQEDIISLWDQSLKPCVKLTPLCVTLN
CKDVNARGEIKNCSFNITTSIRDEVQKEYALFYKLDVVPIDNNNTSYRLI
SCDTSVITQACPKISFEPIPIHYCAPAGFAILKCNDKTFNGKGPCKNVST
VQCTHGIRPVVSTQLLLNGSLAEEEVVIRSDNFTNNAKTIIVQLKESVEI
NCTRPNNNTRKSIHIGPGRAFYTTGEIIGDIRQAHCNISRAKWNDTLKQI
VIKLREQFENKTIVFNHSSGGDPEIVMHSFNCGGEFFYCNSTQLFNSTWN
NNTTEGNTITLPCRIKQIINMWQEVGKAMYAPPIRGQIRCSSNITGLLLT
RDGGINENGTEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRAV
FLGFLGAAGSTMGAASMTLTVQARLLLSGIVQQQNNLLRAIEAQQRMLQL
TVWGIKQLQARVLAVERYLGDQQLLGIWGCSGKLICTTAVPWNASWSNKS
LDRIWNNMTWMEWEREIDNYTSEIYTLIEESQNQQEKNEQELLEL
3D structure
PDB7n6u Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer.
ChainB
Resolution4.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN B E64 S209 E34 S165
BS02 83G B I109 W112 V255 S375 F382 I424 M426 W427 K432 A433 I79 W82 V211 S329 F336 I369 M371 W372 K377 A378
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0006915 apoptotic process
GO:0019049 virus-mediated perturbation of host defense response
GO:0019062 virion attachment to host cell
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0019082 viral protein processing
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046718 symbiont entry into host cell
GO:0075512 clathrin-dependent endocytosis of virus by host cell
GO:1903905 positive regulation of establishment of T cell polarity
GO:1903908 positive regulation of plasma membrane raft polarization
GO:1903911 positive regulation of receptor clustering
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0019031 viral envelope
GO:0020002 host cell plasma membrane
GO:0044174 host cell endosome
GO:0044175 host cell endosome membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7n6u, PDBe:7n6u, PDBj:7n6u
PDBsum7n6u
PubMed34549974
UniProtQ75760

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