Structure of PDB 7n19 Chain B

Receptor sequence
>7n19B (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
RPRFLEYSTSECHFFNGTERVRYLDRYFHNQEENVRFDSDVGEFRAVTEL
GRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFTVQRRVHPKVTVYP
SKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDW
TFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB7n19 CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope.
ChainB
Resolution2.38 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B E9 S11 S13 Y26 Y30 N37 D57 Y60 W61 L67 Q70 K71 R74 Y78 H81 N82 V86 E6 S8 S10 Y23 Y27 N34 D54 Y57 W58 L64 Q67 K68 R71 Y75 H78 N79 V83
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7n19, PDBe:7n19, PDBj:7n19
PDBsum7n19
PubMed34410304
UniProtQ5Y7D1

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