Structure of PDB 7n0z Chain B

Receptor sequence
>7n0zB (length=392) Species: 9606 (Homo sapiens) [Search protein sequence]
DLPLRFPYGRPEFLGLSQDEVEASADHIARPILILKETRRLPWATGYAEV
INAGKSTHNEDQASCEVLTVVSCHYWSLFDGHAGSGAAVVASRLLQHHIT
EQLQDIVDILKKKIPHECLVIGALESAFKEMDLQIERERSSYNISGGCTA
LIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFM
QPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFP
LIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDL
SKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAA
QDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIPLIHGNKL
3D structure
PDB7n0z Structural basis for the specificity of PPM1H phosphatase for Rab GTPases.
ChainB
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B D151 D437 D498 D80 D316 D377
BS02 MN B D151 G152 D80 G81
BS03 MN B D288 D437 D167 D316
Gene Ontology
Molecular Function
GO:0004722 protein serine/threonine phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7n0z, PDBe:7n0z, PDBj:7n0z
PDBsum7n0z
PubMed34580980
UniProtQ9ULR3|PPM1H_HUMAN Protein phosphatase 1H (Gene Name=PPM1H)

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