Structure of PDB 7mys Chain B

Receptor sequence
>7mysB (length=239) Species: 470 (Acinetobacter baumannii) [Search protein sequence]
HVFFAVITLFPEMFDAITAYGISGRAAKRDIVQVTCINPRDFAERRVDER
PFGGGPGMVMMAEPLAKAINHAKQLASRAGCVHVPVVYMSPQGKTLNEQA
VQQFVDYDGLIVLCGRYEGVDERLIQHYVDQEWSIGDYVLSGGELPAMVL
LDSIIRRLPNVQSAIQDSFVDGLLDCPQYTKPDQFEGLDVPEILKSGHHA
NIEKWRFLQRYQRTLERRPELIEQVTLTKQQKKWLSDEQ
3D structure
PDB7mys Crystal structure of a tRNA (guanine-N1)-methyltransferase from Acinetobacter baumannii AB5075-UW bound to S-adenosyl homocysteine
ChainB
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) P93 E120 R158 D173
Catalytic site (residue number reindexed from 1) P91 E118 R156 D167
Enzyme Commision number 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH B S174 D181 S168 D175
BS02 SAH B Y90 M91 S92 P93 G117 Y119 E120 I137 Y140 L142 S143 G144 G145 P148 Y88 M89 S90 P91 G115 Y117 E118 I135 Y138 L140 S141 G142 G143 P146
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0052906 tRNA (guanine(37)-N1)-methyltransferase activity
Biological Process
GO:0002939 tRNA N1-guanine methylation
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mys, PDBe:7mys, PDBj:7mys
PDBsum7mys
PubMed
UniProtB0V8J1|TRMD_ACIBY tRNA (guanine-N(1)-)-methyltransferase (Gene Name=trmD)

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