Structure of PDB 7myp Chain B

Receptor sequence
>7mypB (length=99) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
PQITLWKRPIVTIKIGGQLREALLDTGADDTVLEDIDLPGRWKPKLIVGI
GGFVKVRQYEQVPIEIAGHKVVGTVLIGPTPSNIIGRNLMTQLGATLNF
3D structure
PDB7myp Novel HIV PR inhibitors with C4-substituted bis-THF and bis-fluoro-benzyl target the two active site mutations of highly drug resistant mutant PR S17 .
ChainB
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G04 B D25 G27 D29 V48 G49 I50 D25 G27 D29 V48 G49 I50
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7myp, PDBe:7myp, PDBj:7myp
PDBsum7myp
PubMed34111669
UniProtI7BFC3

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