Structure of PDB 7mtr Chain B

Receptor sequence
>7mtrB (length=760) Species: 9606 (Homo sapiens) [Search protein sequence]
KKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRI
NRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASTAITGVIGGSYSD
VSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMA
EILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMS
RAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDG
WGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFR
EFWEQRFRCSFRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRA
LCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGD
GIGRYNIFTYLRAGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRC
SEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASL
TGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKA
SGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSAL
LTKTNRIARFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPER
REVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIG
FTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPK
LHIILFQPQK
3D structure
PDB7mtr G-protein activation by a metabotropic glutamate receptor.
ChainB
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLU B R57 Y144 S145 A166 T168 Y216 R35 Y98 S99 A120 T122 Y170
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mtr, PDBe:7mtr, PDBj:7mtr
PDBsum7mtr
PubMed34194039
UniProtQ14416|GRM2_HUMAN Metabotropic glutamate receptor 2 (Gene Name=GRM2)

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