Structure of PDB 7ms5 Chain B

Receptor sequence
>7ms5B (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
RQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRY
FDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLA
EHLSHFGIDMLKMQKT
3D structure
PDB7ms5 Structure-Activity Relationship of USP5 Inhibitors.
ChainB
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C199 C202 C219 H232 C26 C29 C46 H59
BS02 ZOG B W209 G220 R221 Y259 Y261 W36 G47 R48 Y86 Y88
BS03 CA B E263 D264 D265 E90 D91 D92
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:7ms5, PDBe:7ms5, PDBj:7ms5
PDBsum7ms5
PubMed34648286
UniProtP45974|UBP5_HUMAN Ubiquitin carboxyl-terminal hydrolase 5 (Gene Name=USP5)

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