Structure of PDB 7mp2 Chain B

Receptor sequence
>7mp2B (length=361) Species: 9913 (Bos taurus) [Search protein sequence]
NHVIFKKISRDKSVTIYLGKRDYIDHVERVEPVDGVVLVDPELVKGKRVY
VSLTCAFRYGQEDIDVMGLSFRRDLYFSQVQVFPPVATTRLQESLIKKLG
ANTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEIKAFATHSTDVEED
KIPKKSSVRLLIRKVQHAPRDMGPQPRAEASWQFFMSDKPLRLAVSLSKE
IYYHGEPIPVTVAVTNSTEKTVKKIKVLVEQVTNVVLYSSDYYIKTVAAE
EAQEKVPPNSSLTKTLTLVPLLANNRERRGIALDGKIKHEDTNLASSTII
KEGIDKTVMGILVSYQIKVKLTVSGLTSSEVATEVPFRLMHPQPEDDENF
VFEEFARQNLK
3D structure
PDB7mp2 Structural evidence for visual arrestin priming via complexation of phosphoinositols.
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 I8P B K15 R171 K298 K300 H301 A381 N384 K7 R159 K286 K288 H289 A356 N359
BS02 I8P B K163 K166 K151 K154
Gene Ontology
Molecular Function
GO:0001664 G protein-coupled receptor binding
Biological Process
GO:0002031 G protein-coupled receptor internalization
GO:0007165 signal transduction
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0005829 cytosol
GO:0016020 membrane
GO:0042995 cell projection

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7mp2, PDBe:7mp2, PDBj:7mp2
PDBsum7mp2
PubMed34678158
UniProtP08168|ARRS_BOVIN S-arrestin (Gene Name=SAG)

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