Structure of PDB 7mmg Chain B

Receptor sequence
>7mmgB (length=187) [Search protein sequence]
KGSVVIVGRINLYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTF
LATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRS
LTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPL
LCPAGHAVGIFRAAVSTRGVAKAVAFIPVESLETTMR
3D structure
PDB7mmg Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance.
ChainB
Resolution1.95 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.21.98: hepacivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZK7 B Q1041 F1043 Y1056 H1057 D1081 L1135 K1136 G1137 S1139 F1154 A1156 A1157 V1158 Q48 F50 Y63 H64 D88 L142 K143 G144 S146 F161 A163 A164 V165
BS02 ZN B C1097 C1099 C1145 H1149 C104 C106 C152 H156
Gene Ontology
Molecular Function
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0019087 transformation of host cell by virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7mmg, PDBe:7mmg, PDBj:7mmg
PDBsum7mmg
PubMed35183560
UniProtA8DG50

[Back to BioLiP]