Structure of PDB 7mk1 Chain B

Receptor sequence
>7mk1B (length=121) Species: 9606 (Homo sapiens) [Search protein sequence]
KENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQ
FSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQ
TLYSKWKDFHFEKIPFDPAEM
3D structure
PDB7mk1 Evolving A RIG-I Antagonist: A Modified DNA Aptamer Mimics Viral RNA.
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B R811 H830 F853 S854 K858 I875 E890 S906 K907 W908 R9 H28 F51 S52 K56 I73 E88 S104 K105 W106
BS02 ZN B C810 C813 C864 C869 C8 C11 C62 C67
External links
PDB RCSB:7mk1, PDBe:7mk1, PDBj:7mk1
PDBsum7mk1
PubMed34487794
UniProtO95786|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)

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