Structure of PDB 7mdi Chain B

Receptor sequence
>7mdiB (length=734) Species: 242231 (Neisseria gonorrhoeae FA 1090) [Search protein sequence]
TDLKVTKRDGRLEAIDLDKIHRVVTWAAEGLENVSVSQVELKSHIQFYNG
IRTDDIHETIIKAAADLISEDTPDYQYLAARLAIFHLRKIAYGEYEPPHL
YNHVKKLTDAGKYDRHILEDYSREEFDELNAYIDHERDMSFSYAAVKQLE
GKYLVQNRVTRQIYETPQFLYVLVAMCLFSKYPKEARLDYVKRFYDAVST
FKVSLPTPIMSGVRTPTRQFSSCVLIECDDSLDSINATTSAIVKYVSQRA
GIGINAGRIRGLDSEIRGGEARHTGCIPFFKMFQAAVKSCSQGGVRGGAA
TLFYPLWHIEAESLLVLKNNRGVEDNRIRQLDYGVQINRLLYTRLIKGGN
ITLFSPNEVSGLYEAFFADQDEFERLYTKYEQDPNIRKRIIPAADLFSTL
MQERAGTGRIYIQNVDHCNTHSPFDPRVAPVHQSNLCMEIALPTKPLDNI
NDPDGEIALCTLSAFNLGALNSLDELEGLADLTVRALDALLDYQGYPVEA
ARTSTMDRRSLGIGVINYAYYLAKNGVRYSDGSALGLTHRTFEAIQYYLL
KASANLAKEYGACTLFNQTVYSQGKLPIDTYKKDLDAVCGEPLHYDWESL
RADIVKYGLRNSTLTALMPSETSSQIANATNGIEPPRGLVTVKASKDGIL
KQVVPEFETLKNAYETLWQLPGNEGYLKLVGVMQKFVDQAISANTAYDPG
KFEGNKVSMKQMLKDLLTAYKYGVKTLYYHNTRD
3D structure
PDB7mdi Effects of chameleon dispense-to-plunge speed on particle concentration, complex formation, and final resolution: A case study using the Neisseria gonorrhoeae ribonucleotide reductase inactive complex.
ChainB
Resolution4.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.17.4.1: ribonucleoside-diphosphate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CDP B P210 T211 C227 R300 L440 C441 S624 E625 T626 S627 P206 T207 C223 R296 L436 C437 S620 E621 T622 S623
BS02 DTP B K11 R12 D20 T57 H61 K7 R8 D16 T53 H57
BS03 DTP B S235 L236 R264 E269 S231 L232 R260 E265
Gene Ontology
Molecular Function
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005524 ATP binding
GO:0016491 oxidoreductase activity
Biological Process
GO:0009263 deoxyribonucleotide biosynthetic process
Cellular Component
GO:0005971 ribonucleoside-diphosphate reductase complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7mdi, PDBe:7mdi, PDBj:7mdi
PDBsum7mdi
PubMed34906669
UniProtQ5F8Z6

[Back to BioLiP]