Structure of PDB 7lro Chain B

Receptor sequence
>7lroB (length=121) Species: 9606 (Homo sapiens) [Search protein sequence]
STEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYG
VIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQC
AEVLESFFVQKLKGFKASRSH
3D structure
PDB7lro Pyridazone inhibitors of BPTF bromodomain
ChainB
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YBV B P2951 F2952 V2956 Y3006 N3007 F3013 P35 F36 V40 Y90 N91 F97
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0016589 NURF complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7lro, PDBe:7lro, PDBj:7lro
PDBsum7lro
PubMed34515477
UniProtQ12830|BPTF_HUMAN Nucleosome-remodeling factor subunit BPTF (Gene Name=BPTF)

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