Structure of PDB 7lrk Chain B

Receptor sequence
>7lrkB (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
SMSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDY
YGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFY
QCAEVLESFFVQKLKGFKASRSH
3D structure
PDB7lrk Pyridazone inhibitors of BPTF bromodomain
ChainB
Resolution1.44 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YC4 B P2951 F2952 V2956 Y3006 N3007 F3013 P37 F38 V42 Y92 N93 F99
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0016589 NURF complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7lrk, PDBe:7lrk, PDBj:7lrk
PDBsum7lrk
PubMed34515477
UniProtQ12830|BPTF_HUMAN Nucleosome-remodeling factor subunit BPTF (Gene Name=BPTF)

[Back to BioLiP]