Structure of PDB 7lpz Chain B

Receptor sequence
>7lpzB (length=201) Species: 9606 (Homo sapiens) [Search protein sequence]
SMSFPPQRYHYFLVLDFEATCDKPQIHPQEIIEFPILKLNGRTMEIESTF
HMYVQPVVHPQLTPFCTELTGIIQAMVDGQPSLQQVLERVDEWMAKEGLL
DPNVKSIFVTCGDWDLKVMLPGQCQYLGLPVADYFKQWINLKKAYSFAMG
CWPKNGLLDMNKGLSLQHIGRPHSGIDDCKNIANIMKTLAYRGFIFKQTS
K
3D structure
PDB7lpz Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases
ChainB
Resolution1.55 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP B F151 E152 A153 C155 Q159 F199 L203 W248 H307 F17 E18 A19 C21 Q25 F65 L69 W114 H173
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:7lpz, PDBe:7lpz, PDBj:7lpz
PDBsum7lpz
PubMed
UniProtO43414|ERI3_HUMAN ERI1 exoribonuclease 3 (Gene Name=ERI3)

[Back to BioLiP]