Structure of PDB 7lnu Chain B

Receptor sequence
>7lnuB (length=261) Species: 1291540 (Methanomethylophilus alvi) [Search protein sequence]
GSHMILIKLGGSVITDKSEYHKFNKETVSRLADEIRRSGQDVMVVHGAGS
FGHVIAKKYAIQDGHVDDGQIPAAARIMCDTRELSSMVVEELLAQGIPAV
SVAPGSCFVMEDGKLIVDNEEPIRRLADLGIMPVMFGDVVPDRKKGFAIV
SGDQCMEVLCRMFDPEKVVFVSDIDGLYTADPKTDKKARLIGEVTRKKLD
EALTDITVADVTGGVHSKMEAMLRMTDRNRRCYLVNGNAPNRLYSLLKGE
TVTCTVAKGGM
3D structure
PDB7lnu Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus .
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.4.26: isopentenyl phosphate kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 IP8 B A45 G49 H50 I146 S148 G149 A48 G52 H53 I149 S151 G152
BS02 ADP B K5 S9 S169 D170 I171 Y175 A177 K180 K215 K8 S12 S172 D173 I174 Y178 A180 K183 K218
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0102043 isopentenyl phosphate kinase activity
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7lnu, PDBe:7lnu, PDBj:7lnu
PDBsum7lnu
PubMed34905349
UniProtM9SEQ1

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