Structure of PDB 7lmw Chain B

Receptor sequence
>7lmwB (length=208) Species: 9606 (Homo sapiens) [Search protein sequence]
GAMAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGG
GPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQ
IPGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEK
GVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPHRALRTA
PIQPRVWE
3D structure
PDB7lmw A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Y6P B R98 Q100 K110 S111 N112 R79 Q81 K91 S92 N93
BS02 Y6P B D73 S74 R77 P87 D54 S55 R58 P68
BS03 Y6P B K62 G70 P71 K43 G51 P52
External links
PDB RCSB:7lmw, PDBe:7lmw, PDBj:7lmw
PDBsum7lmw
PubMed34156100
UniProtQ15109|RAGE_HUMAN Advanced glycosylation end product-specific receptor (Gene Name=AGER)

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