Structure of PDB 7lms Chain B

Receptor sequence
>7lmsB (length=138) Species: 103903 (Coxsackievirus B3 (strain Nancy)) [Search protein sequence]
SGAVYVGNYRVVNRHLATSADWQNCVWESYNRDLLVSTTTAHGCDIIARC
QCTTGVYFCASKNKHYPISFEGPGLVEVQESEYYPRRYQSHVLLAAGFSE
PGDAGGILRCEHGVIGIVTMGGEGVVGFADIRDLLWLE
3D structure
PDB7lms Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3.
ChainB
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C53 C55 C113 H115 C50 C52 C110 H112
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0016032 viral process

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Molecular Function
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Biological Process
External links
PDB RCSB:7lms, PDBe:7lms, PDBj:7lms
PDBsum7lms
PubMed36075902
UniProtP03313|POLG_CXB3N Genome polyprotein

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