Structure of PDB 7lgq Chain B

Receptor sequence

>7lgqB (length=868) Species: 1147 (Synechocystis sp. PCC 6714)

MKILKTLTLRGPNYWSIRRKKLIVMRLDLEDLAERPSNSIPGFYEGLIKV
LPSLVEHFCSPGYQGGFLERVKEGTYMGHIVEHVALELQELVGMTAGFGR
TRETSTPGVYNVVYEYVDEQAGRYAGRAAVRLCRSLVDTGDYPRLELEKD
LEDLRDLGANSALGPSTETIVTEAEARKIPWMLLSARAMVQLGYGVYQQR
IQATLSSHSGILGVELACDKEGTKTILQDAGIPVPRGTTIQYFDDLEEAI
NDVGGYPVVIKPLDGNHGRGITINVRHWQEAIAAYDLAAEESIIVERYYE
GSDHRVLVVNGKLVAVAERIPAHVTGDGSSTISELIEKTNQDPNRGDGHD
NILTKIVVNKTAIDVMERQGYNLDSVLPKDEVVYLRATANLSTGGIAIDR
TDDIHPENIWLMERVAKVIGLDIAGIDVVTSDISKPLRETNGVIVEVNAA
PGFRMHVAPSQGLPRNVAAPVLDMLFPPGTPSRIPILAVTGTNGKTTTTR
LLAHIYRQTGKTVGYTSTDAIYINEYCVEKGDNTGPQSAGVILRDPTVEV
AVLETARGGILRAGLAFDSCDVGVVLNVAADHLGLGDIDTIEQMAKVKSV
IAEVVDPSGYAVLNADDPLVAAMADKVKAKVAYFSMNPDNPIIQAHVRRN
GIAAVYESGYLSILEGSWTLRVEQAKLIPMTMGGMAPFMIANALAACLAA
FVNGLDVEVIRQGVRTFTTSAEQTPGRMNLFNLGQHHALVDYAHNPAGYR
AVGDFVKNWQGQRFGVVGGPGDRRDSDLIELGQIAAQVFDRIIVKEDDDK
RGRSEGETADLIVKGILQENPGASYEVILDETIALNKALDQVEEKGLVVV
FPESVTRAIDLIKVRNPI

3D structure

• PDB: 7lgq Structures and function of the amino acid polymerase cyanophycin synthetase.
• Chain: B
• Resolution: 2.7 Å

Enzymatic activity

• Enzyme Commision number: 6.3.2.29: cyanophycin synthase (L-aspartate-adding).
  6.3.2.30: cyanophycin synthase (L-arginine-adding).

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	G164 P165 S166 Q202 A203 V214 A453 G456	G164 P165 S166 Q202 A203 V214 A449 G452
BS02	peptide	B	D536 T538 Q541 S542 R561 R566	D532 T534 Q537 S538 R557 R562
BS03	ATP	B	N497 G498 K499 T500 N696 D745	N493 G494 K495 T496 N692 D741
BS04	ATP	B	V259 Y303 D307	V259 Y299 D303
BS05	MG	B	T500 T522 E558	T496 T518 E554

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0016874 ligase activity
• GO:0016881 acid-amino acid ligase activity
• GO:0046872 metal ion binding
• GO:0071160 cyanophycin synthetase activity (L-aspartate-adding)
• GO:0071161 cyanophycin synthetase activity (L-arginine-adding)

Biological Process

• GO:0009058 biosynthetic process
• GO:0009059 macromolecule biosynthetic process

External links

• PDB: RCSB:7lgq, PDBe:7lgq, PDBj:7lgq
• PDBsum: 7lgq
• PubMed: 34385683
• UniProt: A0A068N621