Structure of PDB 7lel Chain B

Receptor sequence
>7lelB (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
STVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVK
NPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARM
LQDVFETHFSKIPI
3D structure
PDB7lel Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
ChainB
Resolution2.15 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMF B W293 P294 F295 N297 V299 D300 L304 L306 N352 H356 V358 W29 P30 F31 N33 V35 D36 L40 L42 N88 H92 V94 BindingDB: Kd=172nM
External links
PDB RCSB:7lel, PDBe:7lel, PDBj:7lel
PDBsum7lel
PubMed34710325
UniProtQ58F21|BRDT_HUMAN Bromodomain testis-specific protein (Gene Name=BRDT)

[Back to BioLiP]