Structure of PDB 7las Chain B

Receptor sequence
>7lasB (length=183) Species: 85708 (Porcine circovirus 2) [Search protein sequence]
LSTAVSTLLESGSLVTVAEQHPVTFVRNFRGLAELLKVSGKMQKRDWKTN
VHVIVGPPGCGKSKWAANFADPETTYWKPPRNKWWDGYHGEEVVVIDDFY
GWLPWDDLLRLCDRYPLTVETKGGTVPFLARSILITSNQTPLEWYSSTAV
PAVEALYRRITSLVFWKNATEQSTEEGGQFVTL
3D structure
PDB7las Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus.
ChainB
Resolution4.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B R232 Y233 R276 R277 R114 Y115 R158 R159
BS02 ADP B G177 G179 S181 G59 G61 S63
BS03 MG B S181 D215 S63 D97
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004519 endonuclease activity
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0042025 host cell nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7las, PDBe:7las, PDBj:7las
PDBsum7las
PubMed34311576
UniProtQ6TC59

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