Structure of PDB 7l1p Chain B

Receptor sequence
>7l1pB (length=138) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVITGQETAYFLLKLAGRWP
VKTVHTDNGSNFTSTTVKAACEWAGIKQEFGISMNKELKKIIGQVRDQAE
HLKTAVQMAVFIHNKKRKGGIGGYSAGERIVDIIATDI
3D structure
PDB7l1p HIV Integrase core domain in complex with inhibitor
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 R2A B Q95 E96 A98 Y99 T125 A128 A129 A169 H171 K173 T174 Q36 E37 A39 Y40 T66 A69 A70 A99 H101 K103 T104
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:7l1p, PDBe:7l1p, PDBj:7l1p
PDBsum7l1p
PubMed
UniProtP12497|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol)

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