Structure of PDB 7kws Chain B

Receptor sequence
>7kwsB (length=387) Species: 192222 (Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819) [Search protein sequence]
MKIVIVGIGYVGLANAILFSKNNENEVVLLDIDENKIQSINNHKSPIKDK
LIEKFFVQSKLHATSNIKEAYFNADFAVIATPTDYDENFFDTRSIENVLK
DIKNINSKINVIIKSTVPIGYTKTIKQKFNMSNIVFSPEFLREGSALYDS
LYPSRIIIGDKSVLGKTIGDLFLKNIEKKNVDIFYMDSDEAESVKLFSNT
YLAMRVGFFNEVDSYARKHNLNSADIIKGISADDRIGKYYNNPSFGYGGY
CLPKDTKQLLANFYNIPNSLIKAIVETNEIRKKFITQLILEKKPNILGIY
RLIMKQNSDNFRNSVIIDIIKYLQEYNSNIELIIYEPLVKEKKFLNIKVE
NDFNVFGAKVDLIIANRFDDKLKEIKDKVFSADVFYT
3D structure
PDB7kws Functional and Structural Characterization of the UDP-Glucose Dehydrogenase Involved in Capsular Polysaccharide Biosynthesis from Campylobacter jejuni .
ChainB
Resolution2.09 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T120 E147 K199 N203 C255 D259
Catalytic site (residue number reindexed from 1) T116 E143 K195 N199 C251 D255
Enzyme Commision number 1.1.1.22: UDP-glucose 6-dehydrogenase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003979 UDP-glucose 6-dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0051287 NAD binding
Biological Process
GO:0000271 polysaccharide biosynthetic process
GO:0006065 UDP-glucuronate biosynthetic process
GO:0045227 capsule polysaccharide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7kws, PDBe:7kws, PDBj:7kws
PDBsum7kws
PubMed33621065
UniProtQ0P8H3|UDG_CAMJE UDP-glucose 6-dehydrogenase (Gene Name=kfiD)

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