Structure of PDB 7kv8 Chain B

Receptor sequence
>7kv8B (length=493) Species: 11060 (dengue virus type 2) [Search protein sequence]
MRCIGISNRDFVEGVSGGSWVDIVLEHGSCVTTMAKNKPTLDFELIKTEA
KHPATLRKYCIEAKLTNTTTASRCPTQGEPSLNEEQDKRFVCKHSMVDRG
WGNGCGLFGKGGIVTCAMFTCKKNMEGKVVQPENLEYTIVITPHSGEENA
VGNDTGKHGKEIKVTPQSSITEAELTGYGTVTMECSPRTGLDFNEMVLLQ
MENKAWLVHRQWFLDLPLPWLPGADTQGSNWIQKETLVTFKNPHAKKQDV
VVLGSQEGAMHTALTGATEIQMSSGNLLFTGHLKCRLRMDKLQLKGMSYS
MCTGKFKVVKEIAETQHGTIVIRVQYEGDGSPCKIPFEIMDLEKRHVLGR
LITVNPIVTEKDSPVNIEAEPPFGDSYIIIGVEPGQLKLSWFKKGSSIGQ
MFETTMRGAKRMAILGDTAWDFGSLGGVFTSIGKALHQVFGAIYGAAFSG
VSWTMKILIGVVITWIGMNSTSLSVSLVLVGVVTLYLGVMVQA
3D structure
PDB7kv8 A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6OU B T404 T405 G408 A409 R411 T404 T405 G408 A409 R411
BS02 1Q0 B M412 A413 I414 G416 W420 H437 Y444 Y488 L489 M412 A413 I414 G416 W420 H437 Y444 Y486 L487
Gene Ontology
Molecular Function
GO:0046983 protein dimerization activity

View graph for
Molecular Function
External links
PDB RCSB:7kv8, PDBe:7kv8, PDBj:7kv8
PDBsum7kv8
PubMed34075032
UniProtP18356|POLG_DEN2U Genome polyprotein (Fragment)

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