Structure of PDB 7kgz Chain B

Receptor sequence
>7kgzB (length=634) Species: 301301 (Roseburia hominis) [Search protein sequence]
MRNTIVLEKDWTFYKNPQSESGEAVTLPHTWNAVDGQDGGNDYYRGTCKY
VRHFAKPELEKGGRAYLEFNGAAMTADVVVNGTKLFHHEGGFSTFRVDVT
EQLTEDNLLEVYVDNSDNTKVYPQKADFTFYGGLYRMVKLVTVPKVHFVM
DYAGGNGMKVTPEVTILDAAEKQADADVTVELWMTGEATDVTVAVAGETQ
TVPVENGYARAVFALKNVHLWDGVDDPYLYTAKAELPGGDVVERTFGCRS
FKVDSREGFFLNGRSYPLRGVSRHQDRAGAGNALTYEMHREDMAIVRELG
ANTIRLAHYQHAQEFYDLCDENGIIVWAEIPYITMHMADGTENTLSQMKE
LIVQNYHHPSIVCWGLSNEITAASAVNEELLENHRRLNDLCHELDKTRPT
VMADVFMLETDSPMLEIPDMNSYNLYFGWYIGELDQNDSFFDEYHSTYPD
RVIGLSEYGADANPAYHSANPERGDYTEEYQCVYHEHMAKMIEERPYLWA
THVWNLFDFAADGRDEGGRHGENQKGLVTMDRRIKKDAFYVYKAYWSKAP
FVHLCGSRYTDRAEDVTEIKVYSNQKKVSLFVDGAEKETKEGARIFRFRV
PITGTHTIRAVSGDCTDEITVRKVDEPNPDYIFN
3D structure
PDB7kgz Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B D35 D38 G39 D42 D512 D35 D38 G39 D42 D512
BS02 FMN B Y152 K159 W183 K349 V353 Y356 L394 Y152 K159 W183 K349 V353 Y356 L394
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004565 beta-galactosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7kgz, PDBe:7kgz, PDBj:7kgz
PDBsum7kgz
PubMed35013263
UniProtA0A395V874

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