Structure of PDB 7kdw Chain B

Receptor sequence
>7kdwB (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
MTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEP
MDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLE
SFFVQKLKGFKASR
3D structure
PDB7kdw New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development
ChainB
Resolution1.71 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 WCV B W2950 P2951 F2952 D2960 C3003 F3013 W29 P30 F31 D39 C82 F92
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0016589 NURF complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7kdw, PDBe:7kdw, PDBj:7kdw
PDBsum7kdw
PubMed32588860
UniProtQ12830|BPTF_HUMAN Nucleosome-remodeling factor subunit BPTF (Gene Name=BPTF)

[Back to BioLiP]