Structure of PDB 7kb1 Chain B

Receptor sequence
>7kb1B (length=428) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
DWKKYGYNTRALHAGYEPPEQATGSRAVPIYQTTSYVFRDSDHAARLFAL
EEPGFIYTRIGNPTVSVLEERIAALEEGVGALAVASGQAAITYAILNIAG
PGDEIVSGSALYGGTYNLFRHTLYKKSGIIVKFVDETDPKNIEEAITEKT
KAVYLETIGNPGLTVPDFEAIAEIAHRHGVPLIVDNTVAPYIFRPFEHGA
DIVVYSATKFIGGHGTSIGGLIVDSGKFDWTNGKFPELVEPDPSYHGVSY
VETFKEAAYIAKCRTQLLRDLGSCMSPFNAFLFILGLETLSLRMKKHCEN
ALKIVEFLKSHPAVSWVNYPIAEGNKTRENALKYLKEGYGAIVTFGVKGG
KEAGKKFIDSLTLISHLANIGDARTLAIHPASTTHQQLTEEEQLKTGVTP
DMIRLSVGIEDVEDIIADLDQALRKSQE
3D structure
PDB7kb1 Structures and kinetics of Thermotoga maritima MetY reveal new insights into the predominant sulfurylation enzyme of bacterial methionine biosynthesis.
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WBJ B Y58 R60 Y57 R59
BS02 WBJ B G88 Q89 Y113 N161 D186 S207 T209 K210 N370 R405 G87 Q88 Y112 N160 D185 S206 T208 K209 N369 R404
Gene Ontology
Molecular Function
GO:0003961 O-acetylhomoserine aminocarboxypropyltransferase activity
GO:0004124 cysteine synthase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0030170 pyridoxal phosphate binding
GO:0051009 O-acetylhomoserine sulfhydrylase activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0006535 cysteine biosynthetic process from serine
GO:0009086 methionine biosynthetic process
GO:0019346 transsulfuration
GO:0071266 'de novo' L-methionine biosynthetic process
GO:0071269 L-homocysteine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7kb1, PDBe:7kb1, PDBj:7kb1
PDBsum7kb1
PubMed34019879
UniProtQ9WZY4|METY_THEMA O-acetyl-L-homoserine sulfhydrylase (Gene Name=TM_0882)

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