Structure of PDB 7ka0 Chain B

Receptor sequence
>7ka0B (length=835) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
QSNAMRLPYSWLREVVAVGASGWDVTPGELEQTLLRIGHEVEEVIPLGPV
DGPVTVGRVADIEELTGYKKPIRACAVDIGDRQYREIICGATNFAVGDLV
VVALPGATLPGGFTISARKAYGRNSDGMICSAAELNLGADHSGILVLPPG
AAEPGADGAGVLGLDDVVFHLAITPDRGYCMSVRGLARELACAYDLDFVD
PASNSRVPPLPIEGPAWPLTVQPETGVRRFALRPVIGIDPAAVSPWWLQR
RLLLCGIRATCPAVDVTNYVMLELGHPMHAHDRNRISGTLGVRFARSGET
AVTLDGIERKLDTADVLIVDDAATAAIGGVMGAASTEVRADSTDVLLEAA
IWDPAAVSRTQRRLHLPSEAARRYERTVDPAISVAALDRCARLLADIAGG
EVSPTLTDWRGDPPCDDWSPPPIRMGVDVPDRIAGVAYPQGTTARRLAQI
GAVVTHDGDTLTVTPPSWRPDLRQPADLVEEVLRLEGLEVIPSVLPPAPA
GRGLTAGQQRRRTIGRSLALSGYVEILPTPFLPAGVFDLWGLEADDSRRM
TTRVLNPLEADRPQLATTLLPALLEALVRNVSRGLVDVALFAIAQVVQPT
EQTRGVGLIPVDRRPTDDEIAMLDASLPRQPQHVAAVLAGLREPRGPWGP
GRPVEAADAFEAVRIIARASRVDVTLRPAQYLPWHPGRCAQVFVGESSVG
HAGQLHPAVIERSGLPKGTCAVELNLDAIPCSAPLPAPRVSPYPAVFQDV
SLVVAADIPAQAVADAVRAGAGDLLEDIALFDVFTGPQIGEHRKSLTFAL
RFRAPDRTLTEDDASAARDAAVQSAAERVGAVLRG
3D structure
PDB7ka0 Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.20: phenylalanine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B Q744 D745 S747 D778 F780 Q784 T793 R830 Q748 D749 S751 D782 F784 Q788 T797 R834
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000287 magnesium ion binding
GO:0003723 RNA binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004826 phenylalanine-tRNA ligase activity
GO:0005524 ATP binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0006432 phenylalanyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall
GO:0009328 phenylalanine-tRNA ligase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ka0, PDBe:7ka0, PDBj:7ka0
PDBsum7ka0
PubMed33885823
UniProtP9WFU1|SYFB_MYCTU Phenylalanine--tRNA ligase beta subunit (Gene Name=pheT)

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