Structure of PDB 7k9v Chain B

Receptor sequence
>7k9vB (length=205) Species: 5207 (Cryptococcus neoformans) [Search protein sequence]
QAEISQLLDLIINTFYSNKEIFLRELISNSSDALDKIRYAALTDPSQLDS
EKDLYIRIIPNKEEGTLTIRDTGIGMTKADLVNNLGTIAKSGTKAFMEAL
SSGADISMIGQFGVGFYSSYLVAEKVQVTTKHNDDEQYIWESAAGGTFTI
TEDTEGPRLGRGTSMKLFIKEDLKEYLEEKRIREIVKKHSEFISYPIQLV
VTKET
3D structure
PDB7k9v Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors: Optimization of Whole-Cell Anticryptococcal Activity and Insights into the Structural Origins of Cryptococcal Selectivity.
ChainB
Resolution1.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 W8V B N37 D40 A41 K44 D79 G83 M84 N92 L93 F124 Y125 T171 M173 N29 D32 A33 K36 D71 G75 M76 N84 L85 F116 Y117 T163 M165
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:7k9v, PDBe:7k9v, PDBj:7k9v
PDBsum7k9v
PubMed33444025
UniProtJ9VVA4

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