Structure of PDB 7k7t Chain B

Receptor sequence
>7k7tB (length=386) Species: 9606 (Homo sapiens) [Search protein sequence]
GIRLSTMSPRYLQSNSSSHTRPFSAIAELLDNAVDPDVSARTVFIDVEEV
KNKSCLTFTDDGCGMTPHKLHRMLSFGFTDKPIGVFGNGFKSGSMRLGKD
ALVFTKNGGTLTVGLLSQTYLECVQAQAVIVPIVPFNQQNKKMIIDSLPS
LEAILNYSIFNRENDLLAQFDAIPGKKGTRVLIWNIRRSELDFDTDQYDI
LVSDELPETEYSLRAFCGILYMKPRMKIFLRQKKVTTQMIAKSLANVEYD
TYKPTFTNKQVRITFGFSCFGIMMYHNNRLIKSFEKVGCQVGVGVIGVIE
CNFLKPAYNKQDFEYTKEYRLTINALAQKLNAYWKEKTKVPDQTWVQCDE
CLKWRKLPGIDPSMLPARWFCYYNSHPKYRCSVPEE
3D structure
PDB7k7t Molecular mechanism of the MORC4 ATPase activation.
ChainB
Resolution2.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C429 C432 C453 C464 C348 C351 C371 C381
BS02 ANP B N60 V66 M93 M101 T107 G119 V120 F121 G122 N123 G124 F125 K126 T216 K376 N32 V38 M65 M73 T79 G84 V85 F86 G87 N88 G89 F90 K91 T179 K310
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:7k7t, PDBe:7k7t, PDBj:7k7t
PDBsum7k7t
PubMed33122719
UniProtQ8TE76|MORC4_HUMAN MORC family CW-type zinc finger protein 4 (Gene Name=MORC4)

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