Structure of PDB 7k2k Chain B

Receptor sequence
>7k2kB (length=283) Species: 9606 (Homo sapiens) [Search protein sequence]
LIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYA
VGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIY
AVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVG
GFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYD
GQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHT
FLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
3D structure
PDB7k2k Recapitulating the Binding Affinity of Nrf2 for KEAP1 in a Cyclic Heptapeptide, Guided by NMR, X-ray Crystallography, and Machine Learning.
ChainB
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y334 S363 R380 N382 R415 R483 S508 Y525 S555 Y572 F577 S602 Y8 S37 R54 N56 R89 R157 S182 Y199 S229 Y246 F251 S276
External links
PDB RCSB:7k2k, PDBe:7k2k, PDBj:7k2k
PDBsum7k2k
PubMed33683866
UniProtQ14145|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)

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