Structure of PDB 7k2i Chain B

Receptor sequence
>7k2iB (length=280) Species: 9606 (Homo sapiens) [Search protein sequence]
TAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGG
RNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVG
GSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFD
GTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQD
QLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLD
SVECYDPDTDTWSEVTRMTSGRSGVGVAVT
3D structure
PDB7k2i Recapitulating the Binding Affinity of Nrf2 for KEAP1 in a Cyclic Heptapeptide, Guided by NMR, X-ray Crystallography, and Machine Learning.
ChainB
Resolution2.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y334 S363 R380 N382 R415 R483 S508 Y525 Q530 S555 A556 Y572 F577 S602 Y5 S34 R51 N53 R86 R154 S179 Y196 Q201 S226 A227 Y243 F248 S273
External links
PDB RCSB:7k2i, PDBe:7k2i, PDBj:7k2i
PDBsum7k2i
PubMed33683866
UniProtQ14145|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)

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