Structure of PDB 7k2d Chain B

Receptor sequence
>7k2dB (length=280) Species: 9606 (Homo sapiens) [Search protein sequence]
TAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGG
RNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVG
GSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFD
GTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQD
QLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLD
SVECYDPDTDTWSEVTRMTSGRSGVGVAVT
3D structure
PDB7k2d Recapitulating the Binding Affinity of Nrf2 for KEAP1 in a Cyclic Heptapeptide, Guided by NMR, X-ray Crystallography, and Machine Learning.
ChainB
Resolution2.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y334 S363 R380 N382 R415 R483 S508 G509 Y525 S555 Y572 F577 S602 Y5 S34 R51 N53 R86 R154 S179 G180 Y196 S226 Y243 F248 S273
External links
PDB RCSB:7k2d, PDBe:7k2d, PDBj:7k2d
PDBsum7k2d
PubMed33683866
UniProtQ14145|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)

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