Structure of PDB 7jvk Chain B

Receptor sequence
>7jvkB (length=448) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
LRSTPQDELHDLLCVGFGPASLAIAIALHDALDPRLNKSASNIHAQPKIC
FLERQKQFAWHSGMLVPGSKAQISFIKDLATLRDPRSSFTFLNYLHQKGR
LIHFTNLSTFLPARLEFEDYMRWCAQQFSDVVAYGEEVVEVIPGKSDPSS
SVVDFFTVRSRNVETGEISARRTRKVVIAIGGTAKMPSGLPQDPRIIHSS
KYCTTLPALLKDKSKPYNIAVLGSGQSAAEIFHDLQKRYPNSRTTLIMRD
SAMRPSDDSPFVNEIFNPERVDKFYSQSAAERQRSLLADKATNYSVVRLE
LIEEIYNDMYLQRVKNPDETQWQHRILPERKITRVEHHGPQSRMRIHLKS
SKETLEVDALMVATGYNRNAHERLLSKVQHLRPTGQDQWKPHRDYRVEMD
PSKVSSEAGIWLQGCNERTHGLSDSLLSVLAVRGGEMVQSIFGEQLER
3D structure
PDB7jvk Structural Determinants of Flavin Dynamics in a Class B Monooxygenase.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.196: L-ornithine N(5)-monooxygenase [NAD(P)H].
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B G46 G48 P49 A50 E83 R84 Q85 W90 H91 E167 V168 I210 G211 N323 Y324 S466 G16 G18 P19 A20 E53 R54 Q55 W60 H61 E137 V138 I180 G181 N293 Y294 S425
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004497 monooxygenase activity
GO:0004499 N,N-dimethylaniline monooxygenase activity
GO:0005506 iron ion binding
GO:0031172 ornithine N5-monooxygenase activity
GO:0070401 NADP+ binding
Biological Process
GO:0006696 ergosterol biosynthetic process
GO:0006879 intracellular iron ion homeostasis
GO:0009058 biosynthetic process
GO:0010106 cellular response to iron ion starvation
GO:0019290 siderophore biosynthetic process
GO:0031169 ferrichrome biosynthetic process
GO:0033214 siderophore-dependent iron import into cell
GO:0044550 secondary metabolite biosynthetic process
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Cellular Component
External links
PDB RCSB:7jvk, PDBe:7jvk, PDBj:7jvk
PDBsum7jvk
PubMed33226785
UniProtE9QYP0|SIDA_ASPFU L-ornithine N(5)-monooxygenase (Gene Name=sidA)

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