Structure of PDB 7h8y Chain B

Receptor sequence
>7h8yB (length=159) Species: 37124 (Chikungunya virus) [Search protein sequence]
PSYRVKRMDIAKNDEECVVNAANPRGLPGDGVCKAVYKKWPESFKNSATP
VGTAKTVMCGTYPVIHAVGPNFSNYTESEGDRELAAAYREVAKEVTRLGV
NSVAIPLLSTGVYSGGKDRLTQSLNHLFTAMDSTDADVVIYCRDKEWEKK
ISEAIQMRT
3D structure
PDB7h8y Group deposition for crystallographic fragment screening of Chikungunya virus nsP3 macrodomain
ChainB
Resolution1.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
2.7.7.-
2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.48: RNA-directed RNA polymerase.
3.1.3.84: ADP-ribose 1''-phosphate phosphatase.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.1.74: mRNA 5'-phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ISN B K40 W41 C60 K39 W40 C59
BS02 ISN B T111 C143 R144 D145 W148 T110 C142 R143 D144 W147
External links
PDB RCSB:7h8y, PDBe:7h8y, PDBj:7h8y
PDBsum7h8y
PubMed
UniProtQ8JUX6|POLN_CHIKS Polyprotein P1234

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