Structure of PDB 7h1l Chain B

Receptor sequence
>7h1lB (length=156) Species: 64320 (Zika virus) [Search protein sequence]
GETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMWHVTKGAALRSGEGRL
DPYWGDVKQDLVSYCGPWKLDAAWDGLSEVQLLAVPPGERAKNIQTLPGI
FKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAI
TQGKRE
3D structure
PDB7h1l PanDDA analysis group deposition of ZIKV NS2B-NS3 protease
ChainB
Resolution1.535 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
3.4.21.91: flavivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1AJM B T118 D120 G121 I123 T103 D105 G106 I108
BS02 A1AJM B Y130 S135 G151 V155 Y161 Y115 S120 G136 V140 Y146
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:7h1l, PDBe:7h1l, PDBj:7h1l
PDBsum7h1l
PubMed
UniProtQ32ZE1|POLG_ZIKV Genome polyprotein

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