Structure of PDB 7f9v Chain B

Receptor sequence
>7f9vB (length=476) Species: 5811 (Toxoplasma gondii) [Search protein sequence]
TAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDD
EIKKMGVENSYFPMFVSRHKLEEVAWVTHYGDSPLPEKIAIRPTSETIMY
PAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHA
TEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEA
FIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRS
LGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTM
LEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVR
RDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEV
MPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEGAMKTLCIPFDQ
PPMPEGTKCFYTGKPAKRWTLWGRSY
3D structure
PDB7f9v TgPRS with double inhibitors
ChainB
Resolution1.816 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.15: proline--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1TI B R470 E472 K474 Q475 P476 L480 R481 T482 F485 Q555 A557 G590 T592 R594 R125 E127 K129 Q130 P131 L135 R136 T137 F140 Q210 A212 G245 T247 R249
BS02 HFG B E418 P438 T439 E441 R470 W487 F534 H560 E73 P93 T94 E96 R125 W142 F189 H215
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004827 proline-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006433 prolyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f9v, PDBe:7f9v, PDBj:7f9v
PDBsum7f9v
PubMed
UniProtA0A7J6JUK2

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