Structure of PDB 7f9u Chain B

Receptor sequence
>7f9uB (length=483) Species: 5811 (Toxoplasma gondii) [Search protein sequence]
AMVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRF
FDDEIKKMGVENSYFPMFVSRHKLEPEVAWVTHYGDSPLPEKIAIRPTSE
TIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGH
TAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTT
TVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGC
TTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRE
LKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTA
RVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKIST
FDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEAMTGAMKT
LCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY
3D structure
PDB7f9u TgPRS with double inhibitors
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.15: proline--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HFG B E418 P438 T439 E441 R470 W487 E489 F534 H560 E77 P97 T98 E100 R129 W146 E148 F193 H219
BS02 1TI B E472 P476 L480 R481 T482 R483 F485 W487 Q555 A556 A557 G590 C591 T592 R594 E131 P135 L139 R140 T141 R142 F144 W146 Q214 A215 A216 G249 C250 T251 R253
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004827 proline-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006433 prolyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f9u, PDBe:7f9u, PDBj:7f9u
PDBsum7f9u
PubMed
UniProtA0A7J6JUK2

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