Structure of PDB 7f97 Chain B

Receptor sequence
>7f97B (length=481) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
MAITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAF
FNKEIKKLNVENSYFPLFVTKNKLESPEVAWVTKYGDSNLPEEIAIRPTS
ETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEG
HTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFT
STAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWG
CTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSYCK
DIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNS
CVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVT
SFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLNQTLSGAMKPLC
IPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY
3D structure
PDB7f97 Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with L-proline and compound L97
ChainB
Resolution2.394 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.15: proline--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PRO B T359 E361 W407 E409 H480 W509 G510 T99 E101 W147 E149 H220 W249 G250
BS02 1XK B R390 E392 K394 Q395 P396 I400 R401 T402 F405 Q475 A477 G510 T512 R514 R130 E132 K134 Q135 P136 I140 R141 T142 F145 Q215 A217 G250 T252 R254
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004827 proline-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006433 prolyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f97, PDBe:7f97, PDBj:7f97
PDBsum7f97
PubMed
UniProtQ8I5R7|SYP_PLAF7 Proline--tRNA ligase (Gene Name=proRS)

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