Structure of PDB 7f80 Chain B

Receptor sequence
>7f80B (length=254) Species: 9606 (Homo sapiens) [Search protein sequence]
DLKAFSKHIYNAYLKNFNMTKKKARSILTPFVIHDIETLWQAEKGLVWGL
PPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYG
VHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFA
VKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHL
QANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQE
IYKD
3D structure
PDB7f80 Co-crystal structure of Inhibitor compound in complex with human PPARdelta LBD
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1KF B W228 F246 C249 Q250 T252 T253 H287 L294 L303 V305 I327 I328 K331 H413 Y437 W48 F61 C64 Q65 T67 T68 H102 L109 L118 V120 I142 I143 K146 H228 Y252
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f80, PDBe:7f80, PDBj:7f80
PDBsum7f80
PubMed
UniProtQ03181|PPARD_HUMAN Peroxisome proliferator-activated receptor delta (Gene Name=PPARD)

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