Structure of PDB 7epr Chain B

Receptor sequence

>7eprB (length=310) Species: 32630 (synthetic construct) [Search protein sequence]

KEKILIVGACGQIGSELALALAERYGNTNVITSDIREGGRHNSGTHEMLD
ATDRGELATVVERHKITQVYLLAALLSATGEKNPQWAWNLNMTSLLNVLE
LARQTKIKRVFWPSSIAVFGPTTPKENTPQYTVMEPSTVYGISKQAGEGW
CRWYHANHGVDVRSVRYPGLISWKTPPGGGTTDYAVDIFHAAVTGGKYTC
FLSEDTALPMMYMPDAIRATIELMEAPADKIKIRSSYNLAGMSFTPAQIA
AAIREQIPDFKISYEPDYRQAIADSWPASIDDSVARADWGWKPEFDLKEM
VADMLANLKA

3D structure

PDB

7epr Partial Consensus Design and Enhancement of Protein Function by Secondary-Structure-Guided Consensus Mutations.

Chain

Resolution

2.2 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAD	B	G12 G15 Q16 I17 D38 I39 R40 D54 A55 L76 A77 A78 L94 P117 Y144 K148 Y171 L174	G8 G11 Q12 I13 D34 I35 R36 D50 A51 L72 A73 A74 L90 P113 Y140 K144 Y167 L170

External links

PDB	RCSB:7epr, PDBe:7epr, PDBj:7epr
PDBsum	7epr
PubMed	34254784

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