Structure of PDB 7ela Chain B

Receptor sequence
>7elaB (length=49) [Search protein sequence]
HLGPQFCKSCWAENKGLVECNNHYLCLNCLTLLLGVSSRCPICKMPLPT
3D structure
PDB7ela Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals.
ChainB
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C31 C34 C50 C53 C7 C10 C26 C29
BS02 ZN B C44 H47 C20 H23
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0039702 viral budding via host ESCRT complex
GO:0046761 viral budding from plasma membrane
Cellular Component
GO:0016020 membrane
GO:0020002 host cell plasma membrane
GO:0030430 host cell cytoplasm
GO:0044220 host cell perinuclear region of cytoplasm
GO:0044423 virion component

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7ela, PDBe:7ela, PDBj:7ela
PDBsum7ela
PubMed34127846
UniProtA0A097F4I8

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