Structure of PDB 7ela Chain B
Receptor sequence
>7elaB (length=49) [
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HLGPQFCKSCWAENKGLVECNNHYLCLNCLTLLLGVSSRCPICKMPLPT
3D structure
PDB
7ela
Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals.
Chain
B
Resolution
3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
ZN
B
C31 C34 C50 C53
C7 C10 C26 C29
BS02
ZN
B
C44 H47
C20 H23
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0008270
zinc ion binding
GO:0046872
metal ion binding
Biological Process
GO:0039702
viral budding via host ESCRT complex
GO:0046761
viral budding from plasma membrane
Cellular Component
GO:0016020
membrane
GO:0020002
host cell plasma membrane
GO:0030430
host cell cytoplasm
GO:0044220
host cell perinuclear region of cytoplasm
GO:0044423
virion component
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:7ela
,
PDBe:7ela
,
PDBj:7ela
PDBsum
7ela
PubMed
34127846
UniProt
A0A097F4I8
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