Structure of PDB 7e9k Chain B

Receptor sequence
>7e9kB (length=521) Species: 9913 (Bos taurus) [Search protein sequence]
APALRYPKALQILTEGGTHMVCTGRTHTDRLCRFKWLCYSSEAEEFIFFH
GNASVMLPSLGSRRFQPALLDLSTVEDHNTQYFNFVELPAAALRFMPKPV
FVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAREARLFFMEGW
GEGAHFDLYKLLSPKQPLLRAQLKALGRLLCFSHAFVGLSKVTTWYQYGF
VQPQGPKANILVSGNEIRQFAHFLMEKLNVSQEEYILVFSRTQNRLILNE
AELLLALAQEFQMKTVTVSLEDHAFADVVRLVSNASMLVSMHGAQLVTAL
FLPRGAAVVELFPYAVNPDHYTPYKTLATLPGMDLQYIAWQNTMPENTVT
HPERPWDQGGIAHLDRAEQARILQSREVPRHLCCRNPEWLFRIYQDTKVD
IPSLIQTIRRVVKGHPGPQKWTVSLYPGKVREARCQASSEARLSVSWQIP
WNLKYLKVREVKYEVWLQEQGENTYVPYMLALQNHTFTENIKPFTTYLVW
IRCIFNKTLLGPFADVLVCST
3D structure
PDB7e9k The structure of POMGNT2 provides new insights into the mechanism to determine the functional O-mannosylation site on alpha-dystroglycan.
ChainB
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.312: protein O-mannose beta-1,4-N-acetylglucosaminyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B N532 Y534 W559 N473 Y475 W500
BS02 UDP B N163 L164 R294 Q296 N297 R298 E324 G346 A347 Y447 N116 L117 R241 Q243 N244 R245 E271 G293 A294 Y394
Gene Ontology
Molecular Function
GO:0008375 acetylglucosaminyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0097363 protein O-acetylglucosaminyltransferase activity
Biological Process
GO:0001764 neuron migration
GO:0006486 protein glycosylation
GO:0006493 protein O-linked glycosylation
GO:0035269 protein O-linked mannosylation
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7e9k, PDBe:7e9k, PDBj:7e9k
PDBsum7e9k
PubMed33893702
UniProtQ5NDF2|PMGT2_BOVIN Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (Gene Name=POMGNT2)

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