Structure of PDB 7dj1 Chain B

Receptor sequence
>7dj1B (length=490) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
REHWATRLGLILAMAGNAVGLCNFLRFPVQAAENGGGAFMIPYIIAFLLV
GIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVV
AIYYVYIESWTLGFAIKFLVGLVPEPPPDPDSILRPFKEFLYSYIGVPKG
DEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAV
FLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSL
GFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFG
VANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSI
AIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWA
GTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITP
AFLAVLLVVWATHWTVWITRFYIIGLFLFLTFLVFLAERR
3D structure
PDB7dj1 Crystal structures of LeuT reveal conformational dynamics in the outward-facing states.
ChainB
Resolution3.528 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LEU B A22 G24 L25 C26 F253 T254 S256 F259 S355 A18 G20 L21 C22 F246 T247 S249 F252 S348
BS02 NA B A22 V23 N27 T254 N286 A18 V19 N23 T247 N279
BS03 NA B G20 V23 G24 A351 T354 S355 G16 V19 G20 A344 T347 S348
Gene Ontology
Biological Process
GO:0035725 sodium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7dj1, PDBe:7dj1, PDBj:7dj1
PDBsum7dj1
PubMed33811858
UniProtO67854

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